Multiple cutaneous
leiomyoma
A leiomyoma, also known as a fibroid, is a benign smooth muscle tumor that very rarely becomes cancer (0.1%). They can occur in any organ, but the most common forms occur in the uterus, small bowel, and the esophagus. Polycythemia may occur due to ...
s, also known as Pilar leiomyomas,
arise from the
arrectores pilorum
The arrector pili muscles, also known as hair erector muscles, are small muscles attached to hair follicles in mammals. Contraction of these muscles causes the hairs to stand on end, known colloquially as goose bumps (piloerection).
Structure
E ...
muscles, and are made up of a poorly circumscribed proliferation of haphazardly arranged
smooth muscle
Smooth muscle is an involuntary non-striated muscle, so-called because it has no sarcomeres and therefore no striations (''bands'' or ''stripes''). It is divided into two subgroups, single-unit and multiunit smooth muscle. Within single-unit mus ...
fibers located in the
dermis
The dermis or corium is a layer of skin between the epidermis (with which it makes up the cutis) and subcutaneous tissues, that primarily consists of dense irregular connective tissue and cushions the body from stress and strain. It is divided i ...
that appear to infiltrate the surrounding tissue and may extend into the subcutis.
[Freedberg, et al. (2003). ''Fitzpatrick's Dermatology in General Medicine''. (6th ed.). Page 1033. McGraw-Hill. .]
Sometimes associated with
uterine leiomyomas (a combination known as
multiple cutaneous and uterine leiomyomatosis
Multiple may refer to:
Economics
*Multiple finance, a method used to analyze stock prices
*Multiples of the price-to-earnings ratio
*Chain stores, are also referred to as 'Multiples'
* Box office multiple, the ratio of a film's total gross to th ...
, MCUL), these lesions may also be a manifestation of the
hereditary leiomyomatosis and renal cell cancer
Reed's syndrome is a rare inherited condition characterised by multiple cutaneous leiomyomas and, in women, uterine leiomyomas. It predisposes for renal cell cancer, an association denominated hereditary leiomyomatosis and renal cell cancer, and ...
syndrome.
See also
*
List of cutaneous conditions
Many skin conditions affect the human integumentary system—the organ system covering the entire surface of the body and composed of skin, hair, nails, and related muscle and glands. The major function of this system is as a barrier against t ...
References
External links
Dermal and subcutaneous growths
{{Dermal-growth-stub